Scientists at Albert Einstein College of Medicine of Yeshiva University have identified a small intracellular protein that helps cells commit suicide. The finding, reported as the "paper of the week" in the January 16th print issue of the Journal of Biological Chemistry, could lead to drugs for combating cancer and other diseases characterized by overproduction of cells. The research was led by the late Dennis Shields, Ph.D., a professor in Einstein's Department of Developmental and Molecular Biology for 30 years, who died unexpectedly in December.In response to stress or as a natural part of aging, many cells undergo programmed suicide, also known as apoptosis. Cancer cells often become immortal and dangerous by developing the ability to suppress apoptosis.
A decade ago apoptosis was thought to be directed solely by the nucleus and mitochondria of cells. Dr. Shields' laboratory was the first to show that a cellular organelle known as the Golgi apparatus also plays a role in apoptosis.
Thursday, January 15, 2009
Zombie Watch: Researchers discover protein that causes cell suicide.
Hmm. Scientists finds a way to cause cells to kill themselves. What could go wrong?? From the Albert Einstein College of Medicine:
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